Education /
Student life

For examinees




Faculty Members

Faculty Members


Drug Innovation Center Lead Exploration Unit

Lin BanghongSpecially Appointed Assosiate Professor

◆High-throughput screening of small molecule compounds
◆In vitro pharmacokinetic (ADME) evaluation
◆In vivo pharmacokinetic (PK) evaluation
◆In vitro cardiotoxicity prediction
We support the above drug discovery research.

Representative achievements

Synthesis and Biological Evaluation of Simplified Ansellone Analogues with Lipophilic Side Chains as HIV-Latency-Reversing Agents
Chemistry (Weinheim an der Bergstrasse, Germany) e202300677

Design and synthesis of 4-acetoxypentanamide derivatives of spliceostatin A and their biological evaluation towards prostate cancer treatment
Bioorganic & medicinal chemistry letters 129333-129333

Celastrol suppresses humoral immune responses and autoimmunity by targeting the COMMD3/8 complex
Science immunology 8(81) eadc9324

Design, Synthesis, and Monoamine Oxidase B Selective Inhibitory Activity of N-Arylated Heliamine Analogues
ACS Medicinal Chemistry Letters

Discovery of Benzylpiperazine Derivatives as CNS-Penetrant and Selective Histone Deacetylase 6 Inhibitors
ACS Medicinal Chemistry Letters 13(7) 1077-1082

Design and synthesis of pyrido[2,3-d]pyrimidine derivatives for a novel PAC1 receptor antagonist
European Journal of Medicinal Chemistry 231 114160-114160

A novel RyR1-selective inhibitor prevents and rescues sudden death in mouse models of malignant hyperthermia and heat stroke
Nature Communications 12(1)

Discovery of peroxisome proliferator-activated receptor α (PPARα) activators with a ligand-screening system using a human PPARα-expressing cell line
Journal of biological chemistry 293(26) 10333-10343

Opposing roles for SNAP23 in secretion in exocrine and endocrine pancreatic cells
Journal of cell biology 215(1) 121-138

Zebu Cattle Are an Exclusive Legacy of the South Asia Neolithic
Molecular Biology and Evolution 27(1) 1-6