About us
Secondary metabolites found in marine medicinal resources (marine invertebrates such as marine sponges, and marine microorganisms) have a variety of chemical structures that are beyond the wisdom of mankind. And, this diversity of chemical structure means that it can selectively bind to various molecules that exist in the organisms, and in fact, many secondary metabolites are used as medicines or drug candidates due to the various biological activities derived from this chemical structural diversity. In recent years, it has also contributed to the advance of chemical biology trying to comprehend such diverse biological activities at the molecular level. In particular, studies on target molecule (binding protein) for biologically active secondary metabolites (biologically active natural products) are attracting attention as an important research leading to the development of new drug targets.
In our laboratory, based on the four pillars: Construction of Evaluation System (Screening System) based on the Latest Biological Knowledge; Exploratory Research on New Biologically Active Natural Products from Our Own Marine Medicinal Resource Library; Total Synthesis of New Biologically Active Natural Products and Synthesis of Analog Compounds; and Mechanism of Action and Target Molecule Analysis of New Biologically Active Natural Products, we aim to seamlessly proceed with these research to provide new medicinal seeds and drug target. The students and young researchers that belong here are expected to grow as professionals with both chemistry and biology perspectives through our research, and to play an active role internationally.
Information
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- Feb. 7, 2024
- International students from Brunei came to our laboratory by OUICP.
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- Jan. 31, 2024
- Ms. Titiruetai Doungwichitrkul (Chulalongkorn University) has returned to Thailand after completing her research for 4 months.
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- Jan. 29, 2024
- Ms. Yumni Haziqah Mohammad (Universiti Brunei Darussalam) has joined our group(Graduate Student Mobility Programme(GSM)).
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- Jan. 1, 2024
- Mr. Azhari Muhammad (Institut Teknologi Bandung) has returned to Indonesia after completing his research for 8 months.
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- Nov. 25, 2023
- Prof. Arai gave a lecture at "Program Kompetisi Kampus Merdeka (PKKM) 2023, Faculty of Mathematics and Natural Sciences Lampung University."
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- Oct. 31, 2023
- Mr. Azhari Muhammad (Institut Teknologi Bandung) received the Best Presenter Award at "International Conference on Contemporary Science and Clinical Pharmacy (ICCSCP) 2023."
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- Oct. 23, 2023
- Mr. Jianyu Lin(D1) and Mr. Kohei Sato(M2) presented their results at "the 10th Meeting of Japanese Society for Extracellular Vesicles."
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- Oct. 17, 2023
- Dr. Ibatayev Zharkyn Abykenovich (S.Seifullin Kazakh Agrotechnical University) has returned to Kazakhstan after completing his research for a year.
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- Oct. 13, 2023
- Ms. Fatin Binti Haji Sauli (Universiti Brunei Darussalam) has returned to Brunei after completing her research for 6 months.
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- Oct. 2, 2023
- Ms. Titiruetai Doungwichitrkul (Chulalongkorn University) has joined our group (Chulalongkorn University, Overseas Research Experience Scholarship for Graduate Student).
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- Sep. 15, 2023
- Mr. Jianyu Lin(D1) presented their results at "the 65th Symposium on the Chemistry of Natural Products."
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- Sep. 10, 2023
- Mr. Michihisa Matsuzaki(M2) presented their results at "the 69th Annual Meeting of the Japanese Society of Pharmacognosy."
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- June. 12, 2023
- Specially Appointed Assistant Prof. Kimishima gave a lecture at UBE Corporation.
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- May. 1, 2023
- Mr. Azhari Muhammad (Institut Teknologi Bandung) has joined our group (Nishimura International Scholarship Foundation Program).
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- Apr. 25, 2023
- Mr. Kohei Sato(M2) received the Outstanding Presentation Award at "the 143th Annual Meeting of the Pharmaceutical Society of Japan."
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- Apr. 22, 2023
- Ms. Fatin Binti Haji Sauli (Universiti Brunei Darussalam) has joined our group (Graduate Student Mobility Programme(GSM)).
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- Mar. 26, 2023
- Specially Appointed Assistant Prof. Kimishima, Mr. Kohei Sato(M1) and Mr. Hiroki Kato(B4) presented their results at "the 143rd Annual Meeting of the Pharmaceutical Society of Japan."
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- Feb. 6, 2023
- International students from Brunei came to our laboratory by OUICP.
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- Oct. 18, 2022
- Dr. Ibatayev Zharkyn Abykenovich (S.Seifullin Kazakh Agrotechnical University) has joined our group (Bolashak Grant Internship Program).
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- Oct. 8, 2022
- Prof. Arai gave a lecture as an invited spearker at "the 72nd conference of the Pharmaceutical Society of Japan Kansai Branch."
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- Jun. 24, 2022
- Specially Appointed Assistant Prof. Kimishima received the Encouragement Award by the Division of Natural Medicines, the Pharmaceutical Society of Japan.
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- Jun. 23, 2022
- Research on Single-step construction of an acetoxypyrroloindole skeleton via tandem iodocyclization/acetoxylation of indoles by Mr. Hiroki Kato(B4) and Specially Appointed Prof. Kimishima has been accepted for publication in Organic & Biomolecular Chemistry.
- Collaboration research with Prof. Saito and Dr. Takemura(Bioresponse Regulation) has been accepted for publication in International Immunology.
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- Apr. 25, 2022
- Collaboration research with Aichi Cancer Center on inhibitor of exosome production from cancer cells has been accepted for publication in Scientific Reports.
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- Apr. 1, 2022
- Updated members.
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- Mar. 9, 2022
- Collaboration research with Lampung University (Indonesia) has been accepted for publication in J.Fungi.
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- Feb. 11, 2022
- Collaboration research with Prof. Takikawa and Associate Prof. Ogura(Tokyo University) has been accepted for publication in Biosci. Biotechnol. Biochem.
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- Jan. 25, 2022
- SAR study for anti-Tuberculosis substance PDOA has been accepted for publication in Marine Drugs.
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- Nov. 25, 2021
- Ms. Hongqiang Lin (Jilin University) has returned to China after completing a year of research in the CSC Joint PhD Study.
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- Nov. 19, 2021
- Prof. Arai gave a lecture as an invited speaker at “The First International Symposium of Japan Society for Halal Science and Technology”.
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- Oct. 30, 2021
- Collaboration research with Lampung University (Indonesia) on new cultivation methods of actinomycetes has been accepted for publication in Fermentation.
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- Aug. 27, 2021
- Research on the synthesis of Trichodermamides B and C by Dr. Kimishima has been accepted for publication in Synlett.
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- Aug. 3, 2021
- Prof. Arai gave a lecture as an invited speaker at “The 3rd International Conference on Fisheries Aquatic Environment Science 2021”.
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- July. 29, 2021
- Prof. Arai gave a talk at “ASEAN network symposium on pharmaceutical sciences”.
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- July. 9 and 13, 2021
- Prof. Arai gave a lecture at “Institut Teknologi Bandung International Virtual Course: Marine Natural Product”.
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- July. 1, 2021
- Ms. Aitani has joined to laboratory as a secretary.
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- Apr. 1, 2021
- Updated members.
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- Feb. 22, 2021
- Waleed’s work has been accepted to Journal of advanced Biomedical and Pharmaceutical Sciences.
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- Jan. 7, 2021
- Prof. Arai gave an invited lecture at the “2020 Dalian University of Technology-Overseas Partner Universities Series Online Exchange Conference”.
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- Dec. 11, 2020
- Hongqiang (CSC Scholarship Program) has joined our group.
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- Dec. 8, 2020
- Tianchang has joined our group.
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- Nov. 9, 2020
- Waleed’s work has been accepted to Marine Drugs.
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- Nov. 4, 2020
- Violeta (MEXT Student) has joined our group.
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- Oct. 20, 2020
- Our article on marine-derived fungal diketopiperazine published in Journal of Antibiotics has been selected as the highlighted article.
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- Oct. 19, 2020
- We have renewed our website of Laboratory of Natural Products for Drug Discovery.