Top業績原著論文

原著論文 2011

1. Structure-activity relationship of T-cell receptors based on alanine scanning
Shogo Narimatsu, Yasuo Yoshioka, Tomohiro Morishige, Xing-Lei Yao, Shin-ichi Tsunoda, Yasuo Tsutsumi, Michael I. Nishimura, Yohei Mukai, Naoki Okada, and Shinsaku Nakagawa
Biochem. Biophys. Res. Commun. 415(4): 558-562 (2011)


2. Induction of endoplasmic reticulum-endosome fusion for antigen cross-presentation induced by poly (γ-glutamic acid) nanoparticles.
Yohei Mukai, Tomoyo Yoshinaga, Mai Yoshikawa, Kazuhiko Matsuo, Tomoaki Yoshikawa, Keisuke Matsuo, Kazuyuki Niki, Yasuo Yoshioka, Naoki Okada, and Shinsaku Nakagawa
J. Immunol. 187(12): 6249-6255 (2011)


3. Compositional optimization and safety assessment of a hydrogel patch as a transcutaneous immunization device.
Kazuhiko Matsuo, Yumiko Ishii, Ying-Shu Quan, Fumio Kamiyama, Hideo Asada, Yohei Mukai, Naoki Okada, and Shinsaku Nakagawa
Biol. Pharm. Bull. 34(12): 1835-1840 (2011)


4. Lysine-deficient lymphotoxin-α mutant for site-specific PEGylation.
Shogo Narimatsu, Yasuo Yoshioka, Hikaru Watanabe, Takashi Masano, Tomohiro Morishige, Xing-Lei Yao, Aya Tanabe, Shin-ichi Tsunoda, Yasuo Tsutsumi, Yohei Mukai, Naoki Okada, and Shinsaku Nakagawa
Cytokine 56(2): 489-493 (2011)


5. Tumor vascular targeted delivery of polymer-conjugated adenovirus vector for cancer gene therapy.
Xing-Lei Yao, Yasuo Yoshioka, Tomohiro Morishige, Yusuke Eto, Shogo Narimatsu, Yasuaki Kawai, Hiroyuki Mizuguchi, Jian-Qing Gao, Yohei Mukai, Naoki Okada, and Shinsaku Nakagawa
Mol. Ther. 19(9): 1619-1625 (2011)


6. Intranasal immunization with poly(γ-glutamic acid) nanoparticles entrapping antigenic proteins can induce potent tumor immunity.
Keisuke Matsuo, Hayato Koizumi, Yumiko Ishii, Kazuhiko Matsuo, Takuya Fujita, Akira Yamamoto, Mitsuru Akashi, Shinsaku Nakagawa, and Naoki Okada
J. Control. Release 152(2): 310-316 (2011)


7. Modifying the antigen-immunization schedule improves the variety of monoclonal antibodies obtained from immune-phage antibody libraries against HIV-1 Nef and Vif.
Mai Yoshikawa, Yohei Mukai, Shin-ichi Tsunoda, Yasuo Tsutsumi, Yasuo Yoshioka, Naoki Okada, and Shinsaku Nakagawa
J. Biosci. Bioeng. 111(5): 597-599 (2011)


8. Characterization of transdermal protein delivery by a hydrogel patch in animal, human, and tissue-engineered skin models.
Kazuhiko Matsuo, Yumiko Ishii, Ying-Shu Quan, Fumio Kamiyama, Yohei Mukai, Naoki Okada, and Shinsaku Nakagawa
Biol. Pharm. Bull. 34(4): 586-589 (2011)


9. Effective transcutaneous immunization by antigen-loaded flexible liposome in vivo.
Ni Li, Li-Hua Peng, Xi Chen, Shinsaku Nakagawa, and Jian-Qing Gao
Int. J. Nanomedicine 6: 3241-3250 (2011)


10. Transcutaneous vaccination using a hydrogel patch induces effective immune responses to tetanus and diphtheria toxoid in hairless rat.
Kazuhiko Matsuo, Yumiko Ishii, Ying-Shu Quan, Fumio Kamiyama, Yohei Mukai, Yasuo Yoshioka, Naoki Okada, and Shinsaku Nakagawa
J. Control. Release 149(1): 15-20 (2011)


11. Therapeutic effect of PEGylated TNFR1-selective antagonistic mutant TNF in experimental autoimmune encephalomyelitis mice.
Tetsuya Nomura, Yasuhiro Abe, Haruhiko Kamada, Hiroko Shibata, Hiroyuki Kayamuro, Masaki Inoue, Tomoyuki Kawara, Shuhei Arita, Takeshi Furuya, Takuya Yamashita, Kazuya Nagano, Tomoaki Yoshikawa, Yasuo Yoshioka, Yohei Mukai, Shinsaku Nakagawa, Madoka Taniai, Tsunetaka Ohta, Satoshi Serada, Tetsuji Naka, Shin-ichi Tsunoda, Yasuo Tsutsumi
J. Control. Release 149(1): 8-14 (2011)


12. Development of an antibody proteomics system using a phage antibody library for efficient screening of biomarker proteins.
Sunao Imai, Kazuya Nagano, Yasunobu Yoshida, Takayuki Okamura, Takuya Yamashita, Yasuhiro Abe, Tomoaki Yoshikawa, Yasuo Yoshioka, Haruhiko Kamada, Yohei Mukai, Shinsaku Nakagawa, Yasuo Tsutsumi, Shin-ichi Tsunoda
Biomaterials 32(1): 162-169 (2011)


13. Systemic distribution, nuclear entry and cytotoxicity of amorphous nanosilica following topical application.
Hiromi Nabeshi, Tomoaki Yoshikawa, Keigo Matsuyama, Yasutaro Nakazato, Kazuhiko Matsuo, Akihiro Arimori, Masaaki Isobe, Saeko Tochigi, Sayuri Kondoh, Toshiro Hirai, Takanori Akase, Takuya Yamashita, Kohei Yamashita, Tokuyuki Yoshida, Kazuya Nagano, Yasuhiro Abe, Yasuo Yoshioka, Haruhiko Kamada, Takayoshi Imazawa, Norio Itoh, Shinsaku Nakagawa, Tadanori Mayumi, Shin-ichi Tsunoda, Yasuo Tsutsumi
Biomaterials 32(11): 2713-2724 (2011)


14. Enhanced in vivo gene transfer into the placenta using RGD fiber-mutant adenovirus vector.
Kazufumi Katayama, Rie Furuki, Hideaki Yokoyama, Makoto Kaneko, Masashi Tachibana, Ichiro Yoshida, Hisamitsu Nagase, Keiichi Tanaka, Fuminori Sakurai, Hiroyuki Mizuguchi, Shinsaku Nakagawa, Tsuyoshi Nakanishi
Biomaterials 32(17): 4185-4193 (2011)
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