2015201420132012|2011|201020092008
 
  2011年度

Yamashita K., Yoshioka Y., Higashisaka K., Mimura K., Morishita Y., Nozaki M., Yoshida T., Ogura T., Nabeshi H., Nagano K., Abe Y., Kamada H., Monobe Y., Imazawa T., Aoshima H., Shishido K., Kawai Y., Mayumi T., Tsunoda S., Itoh N., Yoshikawa T., Yanagihara I., Saito S., Tsutsumi Y.
Silica and titanium dioxide nanoparticles cause pregnancy complications in mice.
Nat. Nanotechnol., 6:321-328, 2011. [PubMed]

Higashisaka K., Yoshioka Y., Yamashita K., Morishita Y., Fujimura M., Nabeshi H., Nagano K., Abe Y., Kamada H., Tsunoda S., Yoshikawa T., Itoh N., Tsutsumi Y.
Acute phase proteins as biomarkers for predicting the exposure and toxicity of nanomaterials.
Biomaterials., 32(1):3-9, 2011.<Leading Opinion Paper> [PubMed]

Imai S., Nagano K., Yoshida Y., Okamura T., Yamashita T., Abe Y., Yoshikawa T., Yoshioka Y., Kamada H., Mukai Y., Nakagawa S., Tsutsumi Y., Tsunoda S.
Development of an antibody proteomics system using a phage antibody library for efficient screening of tumor-related biomarker proteins.
Biomaterials., 32(1):162-169, 2011. [PubMed]

Nomura T., Abe Y., Kamada H., Shibata H., Kayamuro H., Inoue M., Kawara T., Arita S., Furuya T., Yamashita T., Nagano K., Yoshikawa T., Yoshioka Y., Mukai Y., Nakagawa S., Taniai M., Ohta T., Serada S., Naka T., Tsunoda S., Tsutsumi Y.
Therapeutic effect of PEGylated TNFR1-selective antagonistic mutant TNF in experimental autoimmune encephalomyelitis mice.
J. Control. Release., 149(1):8-14, 2011. [PubMed]

Nabeshi H., Yoshikawa T., Matsuyama K., Nakazato Y., Matsuo K., Arimori A., Isobe M., Tochigi S., Kondoh S., Hirai T., Akase T., Yamashita T., Yamashita K., Yoshida T., Nagano K., Abe Y., Yoshioka Y., Kamada H., Imazawa T., Nakagawa S., Mayumi T., Itoh N., Tsunoda S., Tsutsumi Y.
Systemic distribution, nuclear entry and cytotoxicity of amorphous nanosilica following topical application.
Biomaterials., 32(11):2713-2724, 2011. [PubMed]

Yoshida Y., Yamashita T., Nagano K., Imai S., Nabeshi H., Yoshikawa T., Yoshioka Y., Abe Y., Kamada H., Tsutsumi Y., Tsunoda S.
Limited expression of reticulocalbin-1 in lymphatic endothelial cells in lung tumor but not in normal lung.
Biochem. Biophys. Res. Commun., 405(4):610-614, 2011.[PubMed]

Yoshikawa M., Mukai Y., Tsunoda S., Tsutsumi Y., Yoshioka Y., Okada N., Nakagawa S.
Modifying the antigen-immunization schedule improves the variety of monoclonal antibodies obtained from immune-phage antibody libraries against HIV-1 Nef and Vif.
J. Biosci. Bioeng., 111:597-599. [PubMed]

Nabeshi H., Yoshikawa T., Arimori A., Yoshida T., Tochigi S., Kondoh S., Hirai T., Akase T., Nagano K., Abe Y., Kamada H., Tsunoda S., Itoh N., Yoshioka Y., Tsutsumi Y.
Effect of surface properties of silica nanoparticles on their cytotoxicity and cellular distribution in murine macrophages.
Nanoscale Res. Lett., 6(1):93-95, 2011.[PubMed]

Nabeshi H., Yoshikawa T., Matsuyama K., Nakazato Y., Tochigi S., Kondoh S., Hirai T., Akase T., Yamashita T., Yamashita K., Yoshida T., Nagano K., Abe Y., Yoshioka Y., Kamada H., Imazawa T., Itoh N., Tsunoda S., Tsutsumi Y.
Amorphous nanosilica induce endocytosis-dependent ROS generation and DNA damage in human keratinocytes.
Part. Fibre. Toxicol., 8(1):1-10, 2011. [PubMed].

Li X., Kondoh M., Watari A., Hasezaki T., Isoda K., Tsutsumi Y., Yagi K.
Effect of 70-nm silica particles on the toxicity of acetaminophen, tetracycline, trazodone, and 5-aminosalicylic acid in mice.
Pharmazie., 66:282-286, 2011. [PubMed]

Isoda K., Hasezaki T., Kondoh M., Tsutsumi Y., Yagi K.
Effect of surface charge on nano-sized silica particles-induced liver injury.
Pharmazie., 66:282-286, 2011. [PubMed]

Yoshida T., Yoshioka Y., Fujimura M., Yamashita K., Higashisaka K., Morishita Y., Kayamuro H., Nabeshi H., Nagano K., Abe Y., Kamada H., Tsunoda S., Itoh N., Yoshikawa T., Tsutsumi Y.
Promotion of allergic immune responses by intranasally-administrated nanosilica particles in mice.
Nanoscale Res. Lett., 6(1):195-200, 2011. [PubMed]

Abe Y., Yoshikawa T., Inoue M., Nomura T., Furuya T., Yamashita T., Nagano K., Nabeshi H., Yoshioka Y., Mukai Y., Nakagawa S., Kamada H., Tsutsumi Y., Tsunoda S.
Fine tuning of receptor-selectivity for tumor necrosis factor-α using a phage display system with one-step competitive panning.
Biomaterials., 32(23):5498-504, 2011. [PubMed]

Diao Y.Y., Li H.Y., Fu Y.H., Jiang H.L., Tsutsumi Y., Wei Q.C., Gao J.Q.
Doxorubicin-loaded PEG-PCL copolymer micelles enhance cytotoxicity and intracellular accumulation of doxorubicin in adriamycin-resistant tumor cells.
Int. J. Nanomedicine., 6:1-8, 2011.[PubMed]

Hirai T., Yoshikawa T., Nabeshi H., Yoshida T., Tochigi S., Uji M., Ichihashi K., Akase T., Yamashita T., Yamashita K., Nagano K., Abe Y., Kamada H., Tsunoda S., Yoshioka Y., Itoh N., Tsutsumi Y.
Size-dependent immune-modulating effect of amorphous nanosilica particles.
Pharmazie., 66(9): 727–728, 2011. [PubMed]

Nabeshi H., Yoshikawa T., Akase T., Yoshida T., Tochigi S., Hirai T., Uji M., Ichihashi K., Yamashita T., Higashisaka K., Morishita Y., Nagano K., Abe Y., Kamada H., Tsunoda S., Itoh N., Yoshioka Y., Tsutsumi Y.
Effect of amorphous silica nanoparticles on in vitro RANKL-induced osteoclast differentiation in murine macrophages.
Nanoscale Res. Lett.,6:464-468, 2011. [PubMed]

Morishita Y., Yamashita K., Yoshikawa T., Terada Y., Nabeshi H., Yoshioka Y., Itoh N., Tsutsumi Y.
Detection of titanium dioxide particles on frozen tissue sections using synchrotron radiation X-ray fluorescence analysis.
Pharmazie., 66(10):808-9, 2011. [PubMed]

Hasezaki T., Isoda K., Kondoh M., Tsutsumi Y., Yagi K.
Hepatotoxicity of silica nanoparticles with a diameter of 100 nm.
Pharmazie., 66(9): 689-703, 2011.[PubMed]

Narimatsu S., Yoshioka Y., Watanabe H., Masano T., Morishige T., Yao X., Tanabe A., Tsunoda S., Tsutsumi Y., Mukai Y., Okada N., Nakagawa S.
Lysine-deficient lymphotoxin-α mutant for site-specific PEGylation.
Cytokine., 56(2): 489-493, 2011.[PubMed]

Narimatsu S., Yoshioka Y., Morishige T., Yao X., Tsunoda S., Tsutsumi Y., Nishimura MI., Mukai Y., Okada N., Nakagawa S.
Structure?activity relationship of T-cell receptors based on alanine scanning.
Biochem. Biophys. Res. Commun., 415(4): 558-562, 2011.[PubMed]

Kayamuro H., Yoshioka Y., Abe Y., Katayama K., Arita S., Nomura T., Yoshikawa T., Itoh N., Kamada H., Tsunoda S., Tsutsumi Y.
Development of TNF-based mucosal vaccine adjuvant for targeting infectious diseases.
Adv. Exp. Med. Biol., 691:299-304, 2011.[PubMed]

Abe Y., Nomura T., Yoshioka Y., Kamada H., Tsunoda S., Tsutsumi Y.
Anti-inflammatory effects of a novel TNFR1-selective antagonistic TNF mutant on established murine collagen-induced arthritis.
Adv. Exp. Med. Biol., 691:493-500, 2011.[PubMed]

Yoshioka Y., Tsunoda S., Tsutsumi Y.
Development of a novel DDS for site-specific PEGylated proteins.
Chem. Cent. J., 5(25):1-6, 2011. [PubMed]

Tsutsumi Y., Yoshioka Y.
Quantifying the biodistribution of nanoparticles.
Nat. Nanotechnol., 6(12): 755, 2011. [PubMed]

Yoshioka Y., Tsutsumi Y.
Recent topics of NanoTox studies for their safety –Foreword-.
Yakugaku Zasshi., 131(2):193-194, 2011.[PubMed]

Yoshikawa T.
Development of NanoSafety forecasting system from the viewpoint of nanomaterial-protein interaction.
Yakugaku Zasshi., 131(2):209-213, 2011.[PubMed]

Yoshioka Y.
NanoSafety studies of nanomaterials about biodistribution and immunotoxicity.
Yakugaku Zasshi., 131(2):221-224, 2011.[PubMed]

吉岡靖雄, 吉川友章, 堤 康央:PEG化による腫瘍壊死因子TNF-αの体内動態の制御と抗腫瘍効果増強.
遺伝子医学MOOK, 別冊., 258-263, 2011.

吉岡靖雄, 中川晋作, 堤 康央
インフラマソームの活性とシリカ粒子の形状.
生体の科学., 62(3):228-232, 2011.

Nabeshi H., Yoshikawa T., Yoshioka Y., Tsutsumi Y.
Safety evaluation study of nanomaterials aimed at the promotion of the social reception.
Genes and Environment., 33(1): 21-26, 2011.

鍋師裕美,吉岡靖雄,吉川友章,堤 康央
食品分野におけるナノテクノロジーの安全性.
食品衛生研究., 61:27-34, 2011.

東阪和馬, 堤 康央
ナノ安全科学研究の最前線.
月刊『化学』(株式会社化学同人)., 66(8): 72-73, 2011.

森下裕貴, 鍋師裕美, 吉川友章, 吉岡靖雄, 堤 康央
香粧品分野におけるナノマテリアルの安全性に関する国内外の報告.
コスメティックステージ., 5(8):45-49, 2011.

角田慎一, 堤 康央
アジュバントとしてのサイトカインおよびその機能性変異体.
『アジュバント開発研究の新展開』., シーエムシー出版, pp158-163, 2011. .

鎌田春彦, 堤 康央, 角田慎一
自己免疫疾患に対するタンパク医薬とDDS.
『次世代バイオ医薬品の製剤設計と開発技術』., シーエムシー出版, pp163-169, 2011.

吉岡靖雄, 角田慎一, 堤 康央
PEG化TNF-α.
『次世代バイオ医薬品の製剤設計と開発技術』., シーエムシー出版, pp170-176, 2011.

堤 康央
巻頭言.
日本DDS学会季刊誌『プロテインエンジニアリングを利用した次世代バイオ創薬』., 26(6): 565-566, 2011.

堤 康央
編集後記.
日本DDS学会季刊誌『プロテインエンジニアリングを利用した次世代バイオ創薬』., 26(6):pp.650, 2011.

角田慎一, 堤 康央
分子進化技術によるサイトカイン機能改変体の創製とDDS.
日本DDS学会季刊誌『プロテインエンジニアリングを利用した次世代バイオ創薬』., 26(6):604-610, 2011.

齋藤 滋,杉浦真弓,丸山哲夫,田中忠夫,竹下俊行,山田秀人,小澤伸晃,中塚幹也,木村 正,藤井知行,下屋浩一郎,山本樹生,佐田文宏,康 東天,早川 智,一瀬白帝,柳原 格,秦 健一郎,勝山博信,堤 康央,中野有美,福井淳史,杉 俊隆
不育症オーバービュー
産婦人科の実際『不育症特集』., 60(10):1401-1408, 2011.


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