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Publications
2001 -

1) Tadayuki Uno, Akihiro Yukinari, Yoko Moriyama, Yoshinobu Ishikawa, Yoshikazu Tomisugi, James A. Brannigan, and Anthony J. Wilkinson
Engineering a Ligand Binding Pocket into a Four Helix Bundle Protein Cytochrome b562
[PubMed] J. Am. Chem. Soc. 123, 512-513 (2001)
2) Tadayuki Uno, Akihiro Yukinari, Yoshikazu Tomisugi, Yoshinobu Ishikawa, Ryu Makino, James A. Brannigan, and Anthony J. Wilkinson
Cysteine Thiolate Coordination in the Ferrous CO Complex of an Engineered Cytochrome b562
[PubMed] J. Am. Chem. Soc. 123, 2458-2459 (2001)
3) Yoshinobu Ishikawa, Takeshi Yamashita, Yoshikazu Tomisugi, and Tadayuki Uno
Interaction of porphyrins bearing peripheral cationic heterocycles with G-quadruplex DNA
[PubMed] Nucleic Acids Res. Suppl. 1, 107-108 (2001)
4) Yoshinobu Ishikawa, Aya Yamashita, and Tadayuki Uno
Efficient Photocleavage of DNA by Cationic Porphyrin-acridine Hybrids with the Effective Length of Diamino Alkyl Chain
[PubMed] Chem. Pharm. Bull. 49, 287-293 (2001)
5) Naoki Yamakawa, Yoshinobu Ishikawa, and Tadayuki Uno
Solution Properties and Photonuclease Activity of Cationic Bis-porphyrins Linked with a Series of Aliphatic Diamines
[PubMed] Chem. Pharm. Bull. 49, 1531-1540 (2001)
6) Yoshinobu Ishikawa, Naoki Yamakawa, and Tadayuki Uno
Potent DNA Photocleavage by Zinc(II) Complexes of Cationic Bis-porphyrins Linked with Aliphatic Diamine
[PubMed] Bioorg. Med. Chem. 10, 1953-1960 (2002)
7) Tadayuki Uno, Katsumasa Aoki, Tomoko Shikimi, Yumi Hiranuma, Yoshikazu Tomisugi, and Yoshinobu Ishikawa
Copper Insertion Facilitates Water-Soluble Porphyrin Binding to rA.rU and rA.dT Base Pairs in Duplex RNA and RNA.DNA Hybrids
[PubMed] Biochemistry 41, 13059-13066 (2002)
8) Katsumasa Aoki, Yoshinobu Ishikawa, Miyuki Oyama, Yoshikazu Tomisugi, and Tadayuki Uno
Self-Aggregation Inhibits the Photonuclease Activity of Porphyrins
[PubMed] Chem. Pharm. Bull. 51, 899-903 (2003)
9) Tadayuki Uno, Rikiharu Sakamoto, Yoshikazu Tomisugi, Yoshinobu Ishikawa, and Anthony J. Wilkinson
Inversion of Axial Coordination in Myoglobin to Create a "Proximal" Ligand Binding Pocket
[PubMed] Biochemistry 42, 10191-10199 (2003)
10) Tadayuki Uno, Daisuke Ryu, Hiroko Tsutsumi, Yoshikazu Tomisugi, Yoshinobu Ishikawa, Anthony J. Wilkinson, Hideaki Sato, and Takashi Hayashi
Residues in the Distal Heme Pocket of Neuroglobin: Implications for the Multiple Ligand Binding Steps
[PubMed] J. Biol. Chem. 279, 5886-5893 (2004)
11) Taku Yamashita, Yohei Hoashi, Kimiko Watanabe, Yoshikazu Tomisugi, Yoshinobu Ishikawa, and Tadayuki Uno
Roles of Heme Axial Ligands in the Regulation of CO Binding to CooA
[PubMed] J. Biol. Chem. 279, 21394-21400 (2004)
12) Tadayuki Uno
Binding Properties of Water-Soluble Porphyrin with RNA Duplexes
J. Porphyrins Phthalocyanines 8, 503 (2004)
13) Yasuhiro Mie, Chiho Yamada, Georges P-J. Hareau, Saburo Neya, Tadayuki Uno, Noriaki Funasaki, Katsuhiko Nishiyama, and Isao Taniguchi
Functional Evaluation of Heme Vinyl Groups in Myoglobin with Symmetric Protoheme Isomers
[PubMed] Biochemistry 43, 13149-13155 (2004)
14) Taku Yamashita, Yohei Hoashi, Yoshikazu Tomisugi, Yoshinobu Ishikawa, and Tadayuki Uno
The C-Helix in CooA Rolls upon CO Binding to Ferrous Heme
[PubMed] J. Biol. Chem. 279, 47320-47325 (2004)
15) Yasuhiro Mie, Chiho Yamada, Tadayuki Uno, Saburo Neya, Fumio Mizutani, Katsuhiko Nishiyama, and Isao Taniguchi
Notable deuterium effect on the electron transfer rate of myoglobin
[PubMed] Chem. Commun. 2005, 250-252 (2005)
16) Takeshi Yamashita, Tadayuki Uno, and Yoshinobu Ishikawa
Stabilization of Guanine Quadruplex DNA by the Binding of Porphyrins with Cationic Side Arms
[PubMed] Bioorg. Med. Chem. 13, 2423-2430 (2005)
17) Yasuhiro Mie, Fumio Mizutani, Tadayuki Uno, Chiho Yamada, Katsuhiko Nishiyama, and Isao Taniguchi
Direct electrochemistry of engineered cytochrome b562 molecules with a ligand binding pocket
[PubMed] J. Inorg. Biochem. 99, 1245-1249 (2005)
18) Hitomi Sawai, Masatomo Makino, Yasuhisa Mizutani, Takehiro Ohta, Hiroshi Sugimoto, Tadayuki Uno, Norifumi Kawada, Katsutoshi Yoshizato, Teizo Kitagawa, and Yoshitsugu Shiro
Structural Characterization of the Proximal and Distal Histidine Environment of Cytoglobin and Neuroglobin
[PubMed] Biochemistry 44, 13257-13265 (2005)
19) Hatsuo Maeda, Kohei Katayama, Hiromi Matsuno, and Tadayuki Uno
3'-(2,4-Dinitrobenzenesulfonyl)-2',7'-dimethylfluorescein as a Fluorescent Probe for Selenols
[PubMed] Angew. Chem. Int. Ed. 45, 1810-1813 (2006)
20) Yoshinobu Ishikawa, Yoshikazu Tomisugi, and Tadayuki Uno
Molecular modeling of anti-parallel G-quadruplex DNA/TMPyP complexes
[PubMed] Nucleic Acids Symp. Ser. 50, 331-332 (2006)
21) Hatsuo Maeda, Kayoko Yamamoto, Iho Kohno, Leila Hafsi, Norio Itoh, Shinsaku Nakagawa, Naoko Kanagawa, Keiichiro Suzuki, and Tadayuki Uno
Design of A Practical Fluorescent Probe for Superoxide Based on Protection-Deprotection Chemistry of Fluoresceins with Benzenesulfonyl Protecting Groups
[PubMed] Chem. Eur. J. 13, 1946-1954 (2007)
22) Yoshinobu Ishikawa, Naoki Yamakawa, and Tadayuki Uno
Synthetic Control of Interchromophoric Interaction in Cationic Bis-porphyrins toward Efficient DNA Photocleavage and Singlet Oxygen Production in Aqueous Solution
[PubMed] Bioorg. Med. Chem. 15, 5230-5238 (2007)
23) Nobuyuki Nakanishi, Fusako Takeuchi, Sam-Yong Park, Hiroshi Hori, Kohei Kiyota, Tadayuki Uno, and Motonari Tsubaki
Characterization of Heme-Coordinating Histidyl Residues of an Engineered Six-Coordinated Myoglobin Mutant Based on the Reactivity with Diethylpyrocarbonate, Mass Spectrometry, and Electron Paramagnetic Resonance Spectroscopy
[PubMed] J. Biosci. Bioeng. 105, 604-613 (2008)
24) Yoshinobu Ishikawa, Naoki Yamakawa, and Tadayuki Uno
Binding of Cationic Bis-porphyrins Linked with p- or m-Xylylenediamine and Their Zinc(II) Complexes to Duplex DNA
[PubMed] Molecules 13, 3117-3128 (2008)
25) Tadayuki Uno, Shinji Uemura, Shiori Yanagita, Taku Yamashita, and Hiroshi Aoyama
Drug Binding and Metabolizing Properties of Human CYP2D6
J. Biol. Inorg. Chem. 14, S195 (2009)
26) Yoshinobu Ishikawa, Takeshi Yamashita, Satoshi Fujii, and Tadayuki Uno
Zinc(II)-5,10,15,20-tetrakis(α-pyridino-m-tolyl)porphyrin Tetrabromide
MolBank 2009, M637 (2009)
27) Yoshinobu Ishikawa, Takeshi Yamashita, Satoshi Fujii, and Tadayuki Uno
1,1',1'',1'''-[Porphyrin-5,10,15,20-tetrayltetrakis(3,1-phenylenemethylene)]tetraquinolinium Tetrabromide
MolBank 2010, M704 (2010)
28) Azusa Takahashi, Yumiko Saito, Masuo Kondoh, Kyohei Matsushita, Susanne M. Krug, Hidehiko Suzuki, Hirofumi Tsujino, Xiangru Li, Hiroshi Aoyama, Koji Matsuhisa, Tadayuki Uno, Michael Fromm, Takao Hamakubo, and Kiyohito Yagi
Creation and biochemical analysis of a broad-specific claudin binder
[PubMed] Biomaterials 33, 3464-3474 (2012)
29) Tamer Zekry Attia, Taku Yamashita, Masayoshi Miyamoto, Atsushi Koizumi, Yuki Yasuhara, Jun-ichi Node, Yumi Erikawa, Yumi Komiyama, Chiaki Horii, Mayu Yamada, Mahmoud Ahmad Omar, Osama Hassan Abdelmageed, Sayed Mohamed Derayea, and Tadayuki Uno
Comparison of Cytochrome P450 Mediated Metabolism of Three CNS Acting Drugs
[PubMed] Chem. Pharm. Bull. 60, 1544-1549 (2012)
30) Mahmoud A. Omar, Osama H. Abdelmageed, Sayed M. Derayea, Tadayuki Uno, and Tamer Z. Atia
Spectrofluorimetric determination of certain antidepressant drugs in human plasma
J. Anal. Sci. Technol. 2013, 4:5 (2013)
31) Tamer Zekry Attia, Taku Yamashita, Mohamed Abdelkhalek Hammad, Akinori Hayasaki, Takumi Sato, Masayoshi Miyamoto, Yuki Yasuhara, Takashi Nakamura, Yusuke Kagawa, Hirofumi Tsujino, Mahmoud Ahmed Omar, Osama Hassan Abdelmageed, Sayed Mohamed Derayea, and Tadayuki Uno
Effect of Cytochrome P450 2C19 and 2C9 Amino Acid Residues 72 and 241 on Metabolism of Tricyclic Antidepressant Drugs
[PubMed] Chem. Pharm. Bull. 62, 176-181 (2014)
32) Hirofumi Tsujino, Taku Yamashita, Azusa Nose, Kaori Kukino, Hitomi Sawai, Yoshitsugu Shiro, and Tadayuki Uno
Disulfide Bonds Regulate Binding of Exogenous Ligand to Human Cytoglobin
[PubMed] J. Inorg. Biochem. 135, 20-27 (2014)
33) Taku Yamashita, Leila Hafsi, Eri Masuda, Hirofumi Tsujino, and Tadayuki Uno
Ferric Human Neuroglobin Scavenges Superoxide to Form Oxy Adduct
[PubMed] Chem. Pharm. Bull. 62, 613-615 (2014)

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